Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease
- Creator: Singanayagam, Aran , Footitt, Joseph , Marczynski, Matthias , Radicioni, Giorgia , Cross, Michael T. , Finney, Lydia J. , Trujillo-Torralbo, Maria-Belen , Calderazzo, Maria , Zhu, Jie , Aniscenko, Julia , Clarke, Thomas B. , Molyneaux, Philip L. , Bartlett, Nathan W. , Moffatt, Miriam F. , Cookson, William O. , Wedzicha, Jadwiga , Evans, Christopher M. , Boucher, Richard C. , Kesimer, Mehmet , Lieleg, Oliver , Mallia, Patrick , Johnston, Sebastian L.
- Resource Type: journal article
- Date: 2022
Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon
- Creator: Finney, Lydia J. , Glanville, Nicholas , Farne, Hugo , Aniscenko, Julia , Fenwick, Peter , Kemp, Samuel V. , Trujillo-Torralbo, Maria-Belen , Loo, Su Ling , Calderazzo, Maria Adelaide , Wedzicha, Jadwiga A. , Mallia, Patrick , Bartlett, Nathan W. , Johnston, Sebastian L. , Singanayagam, Aran
- Resource Type: journal article
- Date: 2021
Beclomethasone has lesser suppressive effects on inflammation and antibacterial immunity than fluticasone or budesonide in experimental infection models
- Creator: Kamal, Faisal , Glanville, Nicholas , Xia, Wangmingya , Bakhsoliani, Eteri , Aniscenko, Julia , Bartlett, Nathan W. , Edwards, Michael R. , Johnston, Sebastian L. , Singanayagam, Aran
- Resource Type: journal article
- Date: 2020
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations
- Creator: Singanayagam, Aran , Glanville, Nicholas , Zhu, Jie , Trujillo-Torralbo, Maria-Belen , Calderazzo, Maria Adelaide , Grainge, Chris , Loo, Su-Ling , Veerati, Punnam Chander , Pathinayake, Prabuddha S. , Nichol, Kristy S. , Reid, Andrew T. , James, Phillip L. , Girkin, Jason L. , Solari, Roberto , Wark, Peter A. B. , Knight, Darryl A. , Moffatt, Miriam F. , Cookson, William O. , Edwards, Michael R. , Mallia, Patrick , Bartlett, Nathan W. , Johnston, Sebastian L. , Ching, Yee Man , Marcellini, Andrea , Porter, James D. , Toussaint, Marie , Walton, Ross P. , Finney, Lydia J. , Aniscenko, Julia
- Resource Type: journal article
- Date: 2018
A short-term mouse model that reproduces the immunopathological features of rhinovirus-induced exacerbation of COPD
- Creator: Singanayagam, Aran , Glanville, Nicholas , Walton, Ross P. , Aniscenko, Julia , Pearson, Rebecca M. , Pinkerton, James W. , Horvat, Jay C. , Hansbro, Philip M. , Bartlett, Nathan W. , Johnston, Sebastian L.
- Resource Type: journal article
- Date: 2015